Abstract

P 178

Heparinized intraocular acrylic lens in uveitis patients

Nölle B., Westphal G., Roider J.
Klinik für Ophthalmologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel

Objective: Biocompatibility of intraocular lenses is extraordinary important for uveitis patients suffering from cataracta complicata. Until now it is unclear, whether a chemically stable superficial heparinization of hydrophilic intraocular lenses is an advantage in regard to other lens materials.
Methods: Between 01.03.2004 and 01.03.2007 phacoemulsifiaction was performed in 27 patients (29 eyes) suffering from uveitic cataract. In 20 patients a anterior uveitis was diagnosed, intermediate posterior or panuveitis were found in three patients of each group. All patients were free of recurrent uveitis for at least one month. Systemic immunosuppression was performed in ten patients (systemic corticosteroids n=5, Mtx n=5, TNFa inhibitors n=2).
Results: IOL implantation was successfully performed in all eyes. Early postsurgical healing was normal for the IOL, fibrin or cellular deposits on the IOL were seen only in severe uveitis cases and could be managed successfully with intensified local antiinflammatory drops. No explantation of any IOL was necessary until now. The rate of secondary cataract seems normal at 23%. 
Conclusions: The BioVue IOL seems to have a high biocompatibility in cases of uveitic cataract. Whether this IOL is superior to other IOL´s should be analyzed in a prospective randomized multicentric study.

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