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AbstractDO.08.04 Automatic evaluation of anterior chamber depth and corneal thickness with slit-lamp-adapted OCT (SL-OCT) Thannhäuser C. L., Wirbelauer C., Pham D. T.
Department of Ophthalmology, Vivantes Hospital Neukölln, Berlin Objective: The precise knowledge of the anterior chamber depth (ACD) and corneal thickness is relevant to diagnose glaucoma, before cataract surgery and in the field of refractive surgery. The purpose of this study was to verify a new automatic and contactless measurement of these parameters with the SL-OCT.
Methods: Within a prospective study, the ACD of 70 patients were examined using the SL-OCT (OCCD, Heidelberg Engineering), the IOL-MasterTM (IMCD, Zeiss) and the ultrasoundbiometry (USCD, Sonomed). Furthermore, the central corneal thickness was measured with the SL-OCT (OCP) and ultrasoundpachymetry (USP, Quantel Medical). The automatic biometry occured with a first-line-version of the segmentation in the Heyex-program.
Results: The average ACD was 3,28±0,38 mm (OCCD), 3,13±0,41 mm (USCD) and 3,11±0,38 mm (IMCD). The real anterior chamber depth was 2,75±0,38mm (rACD ). The mean intersession coefficient of variation was 0,78% (rACD), 3,14% (USCD) and 0,30% (IMCD). There was a high correlation (P<0,001) within in the measures of ACD of r=0,94 (USCD) and r= 0,86 (IMCD). The mean differences (P<0,001) were 151 µm (OCCD-USCD) and 174 µm (OCCD-IMCD), the limits of agreement were ±420 µm (USCD) and ±567 µm (IMCD), respectively. For corneal pachymetry, the mean results were 531±32 µm (OCP) and 545±35 µm (USP) with a correlation of r=0,94 (P<0,001). The mean coefficient of variation was 1,74% (OCP) and 0,62% (USP).
Conclusions: The automatic biometry of the ACD and pachymetry with SL-OCT showed reliable results. The mean difference to the reference methods was about 5%, with limits of tolerance ranging from 13-17%. The higher resolution and the possibility of determination of real anterior chamber parameters are advantages of SL-OCT. After completing the development, a further improvement of automatic measurement and determination is expected.
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