Abstract

P 196

Functional deficiencies in diabetic patients with frequency doubling technique (FDT) and microperimetry (MP)

Shenoy R.¹, Bialasiewicz A. A.^1, McIlvenny S.², Ganguly S.^3 
1Department of Ophthalmology and School of Ophthalmic Technicians, ²Department of Family Medicine and Public Health, ³Department of Epidemiology and Statistics, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman

Objective: To compare the results of retinal function evaluation in patients with diabetes mellitus type II with varying retinopathy using FDT (Matrix^®, Zeiss-Humphrey) and MP (NIDEK^®- MP-1).
Methods: One eye each of 110 patients (110 eyes) with proven diabetes mellitus type II underwent fluorescein angiography, FDT (5° square pattern grating test object, spatial frequency of 0.5 cycles/degree over 16 points) and MP (10 dB threshold white Goldmann stimulus type II object over 46 points, fixation on a 2º single cross pattern). Test duration and retinal sensitivity of patients was compared to age-matched nondiabetic controls and correlated with the severity of diabetic retinopathy.
Results: Absent retinopathy: 59 eyes (54%), retinopathy: 51 eyes (46%). Of the latter, nonproliferative retinopathy 15 (30%) proliferative vitreoretinopathy 8 (14%), diabetic maculopathy 28 (56%). Defective visual field (FDT), unstable fixation (FDT), and subnormal retinal sensitivity (microperimetry) was significant (p<0.01) in 66 (60%) of the study group (absent retinopathy: 20 (30%), NPDR 13 (20%), diabetic maculopathy 33 (50%)), versus 17 (15%) controls. Prolonged test response of >2 min FDT, and 5 min MP was significant (p<0.01) in 61 (55%) of the study group (absent retinopathy: 21 (34%), NPDR: 16 (26%), diabetic maculopathy: 24 (40%)), versus 11 (10%) controls.
Conclusions: Psychophysical changes correlate with the severity of retinopathy in all patients with diabetes mellitus type II.

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