Abstract

P 068

Extraction of topographical information from visual evoked cortical potentials with three active electrodes

Mazinani B. A. E.¹, Waberski T.², Walter P.^1
1Augenklinik, Universitätsklinikum RWTH Aachen; ²Neurologische Klinik, Universitätsklinikum RWTH Aachen

Objective: To introduce and validate a mathematical model to predict visual evoked potentials at any surface location on the head on the base of a set of three active electrodes.
Methods: From 10 healthy subjects (25-38, mean 29 years) continuous VEPs were recorded via 96 channels. On the base of the recordings at the positions POz’, O1’ and O2’, a source dipole vector was calculated for each time point of the recordings and VEP responses were back projected for any of the 96 electrode positions. Differences between the calculated and the actually recorded responses were corrected using a third order polynomial and quantified by coefficients of variation (CV).
Results: The CV of the mean difference between calculated and recorded responses of the ten subjects was 2,8±1,2%.
Conclusions: The "Mini-Brainmapping" model promises a great amount of additional diagnostic information with minimal additional recording efforts as already optionally suggested in the ISCEV standards with good predictive precision affirmed by low coefficients of variation.

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