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AbstractSA.09.02 Optical coherence tomography findings in hemodialysis patients Pahor D.1, Gračner T.1, Gračner B.1, Hojs R.2
1Department of Ophthalmology, Teaching Hospital Maribor, Maribor, Slovenia, 2Department of Nephrology and Hemodialysis, Teaching Hospital Maribor, Maribor, Slovenia Objective: The aim of the present prospective study was to compare retinal thickness between normal healthy subjects and chronic renal failure patients treated with maintenance hemodialysis (HD), as well as to determine whether there is a correlation between age and duration of HD treatment.
Methods: A total of 24 eyes of 12 HD-patients and 32 eyes of 16 controls underwent optical coherence tomographic scanning (OCT) in the central disc of 6000 um diameter.
Results: The mean retinal thickness was measured in the inner temporal, superior, nasal and inferior quadrants. There was a highly significant difference in inner quadrants between controls and HD-patients (P<0,005). The mean retinal thickness was measured also in all outer quadrants The differences between HD-patients and controls were highly significant (P<0,005). The average reduction in retinal thickness in HD-patients compare to the controls in inner quadrants was 7,9% or 22 um (279 in controls, 257 in HD-patients) in and 7,3% or 17,7 um in outer quadrants (244,5 in controls, 226,8 in HD-patients). The average reduction in all quadrants was 7,7% or 20,1 um (262 in controls, 241,9 in HD-patients). The differences between HD-patients and controls were highly significant in all quadrants (P<0,001). No differences in foveal thickness between controls and HD-patients were found. The reduction of retinal thickness was correlated with age of HD-patients, but not with duration of HD treatment.
Conclusions: OCT revealed significant reduction of retinal thickness in HD-patients. The reduction was significant in all quadrants and was correlated to the age of HD-patients. No differences in foveal retinal thickness were found.
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